Study Inflammation During a 100 Miles

• Conditions: Inflammatory Response

• Registration Number: NCT03256006
• Lead Sponsor: Hôpital Necker-Enfants Malades

Brief Summary

To study per and post effort variations of inflammatory biological markers during a 100 miles

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-10
• Study First Submitted QC: 2017-08-16
• Study First Posted: 2017-08-21
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-01
• Last Update Posted: 2018-08-03
• Study Start: 2018-10-18
• Primary Completion: 2018-10-18
• Study Completion: 2018-10-29

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• adults (age>18years)
• completion of an ultra endurance race (50 miles) during the 2 years before

Exclusion Criteria

• female
• age<18years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Variation per and post effort of interleukin 10 plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of interleukin 10 will be measured
Variation per and post effort of lipids plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of lipids
Variation per and post effort of lipoproteins plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of lipoproteins
Variation per and post effort of interleukin 1 plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of interleukin 1 will be measured
Variation per and post effort of interleukin 6 plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of interleukin 6 will be measured
Variation of per and post effort of protein C reactive	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of protein C reactive will be measured
Variation per and post effort of interleukin 4 plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of interleukin 4 will be measured
Variation per and post effort of interleukin 13 plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of interleukin 13 will be measured
Variation per and post effort of interleukin Tumor Necrosis Factor alpha	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of tumor necrosis alpha will be measured
Variation per and post effort of interleukin tumor growth factor beta plasma level	Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race	Plasma level of per and post effort of tumor growth factor beta