OBSERVATION OF HAEMODYNAMIC RESPONSE TO PREGABALINE IN LAPROSCOPIC CHOLECYSTECTOMY SURGERY
Not Applicable
Completed
- Conditions
- Health Condition 1: null- american society of anaesthesiology physical status 1 and 2
- Registration Number
- CTRI/2018/06/014428
- Lead Sponsor
- kasturba medical college manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
.ASA grade 1 & 2 .Aged 18 to 65 years
.Undergoing elective laparoscopic cholecystectomy under general anaesthesia. .CO2 pneumoperitoneum of atleast 30 minutes duration
Exclusion Criteria
1)Known or suspected allergy to Pregabalin.
2)History of uncontrolled hypertension
3)ASA PS 3/4 patients
4)Cognitive impairement, h/o dizziness
5)Currently using sedatives or anti convulsants
6)Preoperative anticipated difficult air way
7)Layngoscopy duration of >30 seconds or more than 1 attempt of laryngoscopy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To observe the efficacy of preoperative oral pregabalin 150 mg on the haemodynamic response to laryngoscopy, intubation and carboperitoneum during laparoscopic cholecystectomyTimepoint: 1)Before premedication <br/ ><br>2)1 hour after premdication <br/ ><br>3)Following intubation <br/ ><br>4)1st minute <br/ ><br>5)2nd minute <br/ ><br>6)3rd minute <br/ ><br>7)4th minute <br/ ><br>8)5th minute <br/ ><br>9)Before carboperitoneum <br/ ><br>10)Following carboperitoneum, <br/ ><br>11)5 minutes <br/ ><br>12)10 minutes <br/ ><br>13)15 minutes <br/ ><br>14)30 minutes <br/ ><br>15)15 minutes following extubation
- Secondary Outcome Measures
Name Time Method SedationTimepoint: 1)Before premedication, <br/ ><br>2)1 hour after premedication, <br/ ><br>3)15 minutes following extubation