NCT02626806Unknown不适用
Exercise-induced High-sensitivity Troponin Levels as a Predictor for Obstructive Coronary Artery Disease
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Presence of coronary artery stenosis more than 50%
研究概览
简要总结
- To compare hs-TnT levels after a cardiac stress test in patients with vs. patients without CAD
- To assess the level of post-exercise hs-TnT predicting CAD (using ROC-analysis)
- To determine the sensitivity, specificity and accuracy of this exercise-induced hsTopT level in predicting CAD, either alone or in relation to traditional patient-related and exercise test-related metrics
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with suspected CAD, planned for diagnostic coronary angiogram
- •Patients with previous revascularization, suspected of recurrent ischemia
排除标准
- •Congestive cardiomyopathy with LV EF < 35%
- •Renal failure with eGFR < 30 ml/min
- •Known structural or severe valvular heart disease
- •Previous ACS < 6 weeks
- •Known incomplete revascularization after previous PCI
- •Unstable angina or ACS (defined as unstable anginal symptoms + ECG changes or hs-TnT > 0.053 ng/L)
结局指标
主要结局
Presence of coronary artery stenosis more than 50%
时间窗: 24 hours
次要结局
未报告次要终点
研究者
Prof Dr Walter Desmet
Head of Clinic, Interventional Cardiology
Universitaire Ziekenhuizen KU Leuven
研究点 (1)
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