Randomised controlled trial of Bilamellar Tarsal Rotation (BLTR) verses Posterior Lamellar Tarsal Rotation (PLTR) surgery for trachomatous trichiasis
Not Applicable
- Conditions
- Eye DiseasesSurgeryTrachoma, Trichiasis
- Registration Number
- PACTR201401000743135
- Lead Sponsor
- ondon School of Hygiene and Tropical Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
Case Definition:
Trachomatous Trichiasis cases in this study will be defined as: individuals with one or more eyelashes touching the eyeball or with evidence of epilation in either or both of the eyes, and tarsal conjunctival scarring.
1.Trachomatous Trichiasis with tarsal conjunctival scarring
2.Adults (¿18 years)
3.Agree to be randomly allocated to one of the two alternative operative procedures
4.Agree to re-examination at six and twelve months after surgery
Exclusion Criteria
Exclusion Criteria:
1.Age less than 18 years
2.Previous eyelid surgery
3.Medically unfit, BP systolic >170, diastolic >110.
4.Pregnant
5.Patients with trichiasis from other eyelid pathologies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome measure: recurrent trichiasis, defined as one or more lashes touching the eye or clinical evidence of epilation at either the six or twelve month assessments or a history of repeat surgery during the last one year after the baseline surgery
- Secondary Outcome Measures
Name Time Method Secondary outcome measures: (1) Severity of recurrent trichiasis (number of lashes) and entropion, (2) Change in corneal opacification (by comparison of photographs), (3) Change in visual acuity (LogMAR), (4) Conjunctival inflammation, (5) Complication rates