Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

Not Applicable

Completed

• Conditions: Parkinson Disease

• Registration Number: NCT00004451
• Lead Sponsor: National Institute of Mental Health (NIMH)

Brief Summary

This study will determine whether glucose facilitates memory in healthy elderly people and those with Parkinson's disease.

Detailed Description

Subjects fast for 8 hours before receiving a test to determine their blood glucose levels. Following this test, subjects are randomized to receive either a glucose or saccharin sweetened drink. A series of memory tests and an additional 3 blood glucose level tests are administered approximately 15 minutes later. A minimum of 1 week afterward, the subjects return and receive the alternate sweetener followed by additional memory tests.

Study Timeline

• Study Start: 1998-03
• Study First Submitted: 1999-10-18
• Study First Submitted QC: 1999-10-18
• Study First Posted: 1999-10-19
• Status Verified: 2005-11
• Last Update Submitted: 2005-11-29
• Last Update Posted: 2005-12-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Three groups of subjects are eligible for this study: Healthy young adults between ages 18 and 30; Healthy elderly adults between ages 60 and 90; AND Anyone diagnosed with Parkinson's disease

Exclusion Criteria

• Prior surgery to remove part of the stomach
• Diabetes, Addison's, or Cushing's diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University of Virginia; 🇺🇸 Charlottesville, Virginia, United States