Subclinical cerebellar dysfunction in patients with migraine

• Conditions: headache; 10019231

• Registration Number: NL-OMON31417
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Patients with migraine and aura with minimal 6 attacks a year (2 with aura).
Healthy volunteers without migraine.
Patients with a cerebellar degenerative diseases

Exclusion Criteria

For the migrainepatients and healthy controls: Neurologic diseases in which the function of cerebellum is disturbed.
The use of medicines/drugs which have influence on the coordination 24 hours before taking part of this examination.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The eye-blink difference between migrainepatients and controls.<br /><br>Parameters: CR/UR amplitude, CR/UR onset, CR/UR Peakamplitude and the CR/UR<br /><br>Peaktime gebruikt (CS= conditioned respons US= unconditioned respons)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The sensitivity of trigeminus system by migrainepatients compared with controls.<br /><br>Do the results of the disturbed conditioned corresponds to a<br /><br>coordinationdisorder measured by the sway-test?<br /><br>The relations between the contols, the migrainepatients and the patients with a<br /><br>degenerative disease.</p><br>