Effects of Time of Day and Nut Intake on Cognitive Performance
- Conditions
- Cognitive Performance
- Interventions
- Other: NutsOther: Nut-free meal
- Registration Number
- NCT06343142
- Lead Sponsor
- Monash University
- Brief Summary
This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance.
- Detailed Description
In this trial, eligible participants will receive isocaloric meals with or without nuts at lunchtime and dinner time. Cognitive performance will be performed before and 90 min after the meals.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
- Non-shift workers
- 18-55 years
- BMI between 18.5 and 27 kg/m2,
- Non-smokers
- Without chronic illnesses
- Allergy to nuts
- BMI<18.5 or >27 kg/m2
- Presence of dementia or psychiatric disease (depression, Parkinson's disease, schizophrenia)
- Presence of diabetes, serious health conditions that may affect participation e.g. liver or thyroid dysfunction, recent major surgery, cardiovascular disease
- Presence of any sleep disorders
- Taking anti-diabetic or lipid-lowering medication
- Do not speak English
- Pregnant or planning on becoming pregnant
- Breastfeeding
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Lunch nut meal Nuts Participants will receive an isocaloric meal with nuts at lunchtime. Lunch nut-free meal Nut-free meal Participants will receive an isocaloric meal without nuts at lunchtime. Dinner nut meal Nuts Participants will receive an isocaloric meal with nuts at dinner. Dinner nut-free meal Nut-free meal Participants will receive an isocaloric meal without nuts at dinner.
- Primary Outcome Measures
Name Time Method N-back task - accuracy before meal x 90 min post-meal Difference in the total accuracy
N-back task - reaction time before meal x 90 min post-meal Difference in the reaction time for correct matched responses
Stroop test - incongruent before meal x 90 min post-meal Difference in the reaction time for incongruent
Stroop test - interference before meal x 90 min post-meal Difference in stroop interference (incongruent - congruent response time)
N-back task - matched responses before meal x 90 min post-meal Difference in the % matched responses
N-back task - false alarm before meal x 90 min post-meal Difference in the % false alarm
Stroop test - congruent before meal x 90 min post-meal Difference in the reaction time for congruent
- Secondary Outcome Measures
Name Time Method Multitasking - mixed blocks before meal x 90 min post-meal Difference in the reaction time for mixed blocks
Satiety - satisfaction Satisfaction will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). Difference in postprandial satisfaction
Satiety - hunger Hunger will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). Difference in postprandial hunger
Satiety - eating capacity Eating capacity will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). Difference in postprandial eating capacity,
Multitasking - pure blocks before meal x 90 min post-meal Difference in the reaction time for pure blocks
Satiety index Satiety index will be assessed before the meal and 4 times after the meal (15, 30, 60 and 90 mins). Difference in postprandial satiety index, calculated using the mean of the four satiety questions, where "hunger" and "eating capacity" will be scored in an inverse way than "fullness" and "satisfaction".
Satiety - fullness Fullness will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). Difference in postprandial fullness
Multitasking - mixing cost before meal x 90 min post-meal Difference in mixing cost (mixed - pure reaction time)
Trial Locations
- Locations (1)
Department of Nutrition, Dietetics and Food - Monash University
🇦🇺Notting Hill, Victoria, Australia