Effects of Subcutaneously Infiltrated Nicardipine on the Success Rate of Radial Artety Cannulation
- Registration Number
- NCT05920538
- Lead Sponsor
- Mahidol University
- Brief Summary
The goal of this study is to compare the success rate of subcutaneously infiltrated nicardipine to normal saline in radial artery cannulation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 190
Inclusion Criteria
- age 18-75 years
- the patient who need to arterial line
Exclusion Criteria
- allergy to nicardipine
- history of peripheral artery disease
- BMI > 40 kg/m2
- unwilling to participate or denial of informed consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Normal saline Normal saline Using normal saline 0.5ml subcutaneously infiltrated by ultrasound before redial artery cannulation Nicardipine Nicardipine Using nicardipine 0.5 mg(0.5ml) subcutaneously infiltrated by ultrasound before redial artery cannulation.
- Primary Outcome Measures
Name Time Method Success rate of radial artery cannulation since first skin puncture 10 minute from puncture at skin Success rate of radial artery cannulation since first skin puncture
- Secondary Outcome Measures
Name Time Method radial artery diameter Pre-induction to 3 minute after subcutaneous infiltration Pre-induction radial artery diameter, post-induction radial artery diameter, radial artery diameter after subcutaneous infiltration at 0,1,2 and 3 minute
Time from first skin puncture to success cannulation 10 minutes Time from first skin puncture to present of arterial wave form, assessed less than 10 minutes
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does nicardipine utilize to improve radial artery cannulation success rates compared to normal saline?
How does subcutaneous nicardipine infiltration compare to other vasodilators in radial artery cannulation efficacy and safety?
Are there specific biomarkers that predict better response to nicardipine infiltration in radial artery cannulation?
What are the potential adverse events associated with nicardipine infiltration for radial artery cannulation and how are they managed?
What other calcium channel blockers or vasodilatory agents are being studied for improving radial artery cannulation success rates?
Trial Locations
- Locations (1)
Anesthesiology Department
🇹🇭Bangkok, Thailand
Anesthesiology Department🇹🇭Bangkok, Thailand