Nicardipine
生产企业：Ekr therapeutics inc, Amneal pharmaceutical，另有 11 家
Nicardipine is a calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
Nicardipine is a calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
By deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, nicardipine inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Used for the management of patients with chronic stable angina and for the treatment of hypertension.
共 4 项相关疾病
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
