Activity of brown adipose tissue and thyroid hormones
Recruiting
- Conditions
- Overgewicht, Obesity, Brown adipose tissue, Bruin vet
- Registration Number
- NL-OMON23019
- Lead Sponsor
- Academic Medical Center (AMC), Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Male sex
- Age between 30 and 40 years old
Exclusion Criteria
- Treated or untreated hypo- or hyperthyroidism
- Renal dysfunction (eGFR >60)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method After TRH administration, compared to saline administration;<br /> <br>- Degree of BAT activity<br /><br>- Skin temperature<br /><br>- Blood pressure and heart rate<br /><br>- Serum thyroid hormones and noradrenaline and normetanephrine
- Secondary Outcome Measures
Name Time Method The association between BAT acitvity and changes in skin temperature, blood pressure, heart rate, and blood parameters.