The prospective trial to validate the effect of continuous infusion of low-dose esmolol on the requirement of inhalation anesthetics and opioid during surgery
Not Applicable
Recruiting
- Conditions
- Diseases of the blood and blood -forming organs and certain disorders involving the immune mechanism
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 56
Inclusion Criteria
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Exclusion Criteria
patients with cardiovascular diseases such as hypertension, arrhythmia, or myocardial ischemia; unstable hemodynamics due to haemorrhage, hypovolemia, or loss of body fluids; asthma or chronic obstructive pulmonary diseases; allergies to the study drug; or body mass index below 16 or over 30 kg/m2, as well as patients requiring opioids for pain diseases and those who refused to participate
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method average effect-site concentration of remifentanil;ratio of average to adequate effect-site concentration of remifentanil;frequency of increase and decrease in the effect-site concentration of remifentanil per hour
- Secondary Outcome Measures
Name Time Method time to awakening & orientation;level of postoperative pain;total dose of fentanyl;length of stay in the PAC