se of intravenous fat emulsion an alternative method of preparing patients for positron emission tomography (PET) imaging of the heart

Phase 4

Completed

• Conditions: Cardiovascular - Coronary heart disease; ormal cardiac function; Heart disease; Normal cardiac function; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12616000279426
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-02
• Study Completion: 2021-06-28
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Aged greater than or equal to 18 years
Available to attend two visits for screening and imaging
Able and willing to complete the informed consent process

Exclusion Criteria

Previous diagnosis of Type I and Type II diabetes mellitus
Previous diagnosis of ischaemic heart disease or ongoing symptoms of chest pain or previous cardiac surgery
Allergies to lipid, glucose, soyabean, peanut or egg
Pregnant or plans to become pregnant or breastfeeding
Inability to lie flat (sleeping on greater than 2 pillows) or known claustrophobia
Judged otherwise unfit by medical officer to participate in the trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Qualitative (visual categoric uptake scale) comparative assessments of 18F-FDG myocardial uptake in both arms[Visit 2 and Visit 3 (likely Day 0 to Day 7)<br>On each of these days:<br>0 minutes - FDG is injected and patient is placed in quiet, dark room<br>60 minutes - PET scan is performed and measurements are taken at that time];Quantitative (minimum standardised uptake value and maximum standardised uptake value) comparative assessments of 18F-FDG myocardial uptake in both arms,[Visit 2 and Visit 3 (likely Day 0 to Day 7)<br>On each of these days:<br>0 minutes - FDG is injected and patient is placed in quiet, dark room<br>60 minutes - PET scan is performed and measurements are taken at that time]