A study on the relationship between hypogonadism and endocrine dysfunction, osteoporosis and lipodystrophy in men with HIV infectio
- Conditions
- Endocrine, nutritional and metabolic disease
- Registration Number
- KCT0003118
- Lead Sponsor
- Keimyung University Dongsan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Male
- Target Recruitment
- 50
1. A male patient aged 19 to 55 who was diagnosed with HIV infection by western blot analysis and was visiting Dongsan Medical Center infectious disease outpatient department
2. Currently on combination antiretroviral therapy (cART)
3. Patients with HIV-RNA less than 50 copies/m
1. Patients currently treated with acute/subacute disease other than HIV infection
2. Patients currently treated with opportunistic infections
3. Patients diagnosed with liver cirrhosis (over C-P criteria A) and severe renal impairment(eGFR <30)
4. Patients who have been diagnosed with congenital hypogonadism or currently undergoing treatment
5. Patients with a history of testosterone, anabolic agents, antiandrogens, estrogens, glucocorticoids, GnRH analog, growth hormone, IGF-1 treatment in 3months
6. Patients who have been diagnosed or currently treated for endocrine disorders that can cause hypogonadism(Hyperprolactinemia, Hypothyroidism, Pituitary disease, Testicular disease, Adrenal disease)
7. Patients previously undergoing pituitary surgery/radiation
8. Patients who have been diagnosed with malignant tumors
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum testosterone level(Total/Free)
- Secondary Outcome Measures
Name Time Method Change of bone mineral density(Lumbar, Femur neck, Femur total);Visceral adiposity index