Influence of Manual Diaphragm Release Combined With Conventional Breathing Exercises and Prone Positioning on Pulmonary Functions in Women With COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- forced vital capacity FVC
研究概览
简要总结
Manual noninvasive respiratory techniques gained interest to treat respiratory pathologies related to COVID 19. This study designed to determine the combined effect of manual diaphragmatic release technique with the effect of conventional breathing exercises and prone positioning on pulmonary function parameters (FVC, FEV1, PEF, FEV1/FVC, FEF25, FEF50, FEF75, FEF25/75).
详细描述
Forty females were randomly assigned to two groups. Group A received manual diaphragm release with conventional breathing exercises and prone positioning. Group B received conventional breathing exercises and prone positioning. Both groups took their prescribed medications. Their ages ranged from 35 to 45 years and with moderate COVID-19 illness. Any cases with mild and severe COVID-19 illness, ICU admission, and chest diseases were excluded.
Main measures: pulmonary function parameters (FVC, FEV1, PEF, FEV1/FVC, FEF25, FEF50, FEF75, FEF25/75).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 35 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women with moderate COVID-19 illness diagnosed by a physician.
- •Patients with o2 saturation >94%Nonsmoker subjects.
- •age ranging from 35-45 years.
- •body mass index from 25 to 34 kg/m2.
排除标准
- •Unstable hemodynamic status.
- •Acute respiratory failure requiring intubation and impaired consciousness.
- •Inability to collaborate with prone positioning with refusal.
- •Change of mental status hindering response to instructions.
- •Poorly controlled hypertension (Mean systolic BP > 140 mmhg and \or diastolic BP > 40 mmhg).
- •Patients who take continuous o2 supplementation.
- •Other chest diseases as (COPD-asthma-tuberculosis-cancer).
- •Male patients.
结局指标
主要结局
forced vital capacity FVC
时间窗: pre study and 3 weeks post study for all participants
the amount of air that can be forcibly exhaled from your lungs after taking the deepest breath possible which is a common breathing test to check lung function.
FEV1/FVC
时间窗: pre study and 3 weeks post study for all participants
FEV1/FVC, also known as FEV1%) can help distinguish obstructive and restrictive lung diseases.
FEV1
时间窗: pre study and 3 weeks post study for all participants
the maximum amount of air that the subject can forcibly expel during the first second following maximal inhalation
PEF
时间窗: pre study and 3 weeks post study for all participants
show the amount and rate of air that can be forcefully breathed out of the lungs.
PEF25%
时间窗: pre study and 3 weeks post study for all participants
Peak expiratory flow at 25% of fvc and the most sensitive measure of airflow in peripheral airways where primary airflow obstruction originates.
PEF50%
时间窗: pre study and 3 weeks post study for all participants
Peak expiratory flow at 50% ofFVC
PEF 75%
时间窗: pre study and 3 weeks post study for all participants
Peak expiratory flow at 75% of FVC
PEF 25%/75%
时间窗: pre study and 3 weeks post study for all participants
Maximum flow rate in the middle 50% of forced expiration.
次要结局
未报告次要终点
研究者
mona abd el raouf ghallab
lecturer at faculty of physical therapy
Cairo University