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A Study of Epoetin Beta (NeoRecormon) in Participants With Solid Tumors

Phase 4
Completed
Conditions
Anemia
Interventions
Registration Number
NCT02554942
Lead Sponsor
Hoffmann-La Roche
Brief Summary

This study will evaluate the safety of subcutaneous (SC) epoetin beta (NeoRecormon) in adults with solid tumors being treated with platinum-based chemotherapy capable of inducing anemia. The anticipated time on study treatment is 16 weeks, and the target sample size is approximately 208 individuals.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
28
Inclusion Criteria
  • Adults at least 18 years of age
  • Presence of solid tumor(s)
  • Receiving platinum-based therapy capable of inducing anemia
Exclusion Criteria
  • Red blood cell transfusion within 7 days prior to study drug
  • Relevant acute or chronic bleeding requiring therapy within 3 months prior to study drug
  • Women who are pregnant or breastfeeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Epoetin betaEpoetin betaParticipants will receive weekly SC injection of epoetin beta (450 international units per kilogram \[IU/kg\]) for 16 weeks.
Primary Outcome Measures
NameTimeMethod
Incidence of adverse eventsUp to 16 weeks
Secondary Outcome Measures
NameTimeMethod
Hemoglobin response rate indexUp to 16 weeks
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