Comparative effects of consuming various whole fruits before meals on fasting blood glucose and insulin levels among patients with type 2 diabetes mellitus in Indonesia

Not Applicable

Completed

• Conditions: Type 2 diabetes mellitus; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN10024302
• Lead Sponsor: Sebelas Maret University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-03-20
• Study Start: 2022-01-20
• Last Update Posted: 1 February 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

1. Aged 30–75 years old
2. Routinely treated by anti-diabetic drugs except for DPP4 inhibitor
3. Able to ingest fresh fruits

Exclusion Criteria

1. Pregnant
2. Smoking
3. Chronic disease (e.g. heart, kidney, liver disease)
4. Insulin and DPP4 inhibitor therapy
5. Not routinely visiting the clinics

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Fasting blood glucose (FBG) levels measured using the enzymatic method (glucose oxidase – peroxidase aminoantypirin) at 1, 7, 14 and 21 days<br> 2. Insulin levels measured using an enzyme-linked immunosorbent assay (ELISA) kit at 1, 7, 14 and 21 days<br> 3. HOMA-ß ratio calculated using the FBG and insulin levels with the formula: (HOMA-ß = 20 X insulin level) / (FBG level – 3.5) at 1, 7, 14 and 21 days.<br> 4. Acetic acid levels determined using gas chromatography-mass spectrometry at 14 and 21 days<br>