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Supplemental oxygen to improve the efficiency of exercise training therapy in type 2 diabetes patients.

Recruiting
Conditions
Diabetes mellitus type 2
Registration Number
NL-OMON21976
Lead Sponsor
Erasmus MCP.O.Box 2040, NL-3000 CA Rotterdamphone: +31 10 703 18 87 / 31 80 (secr)
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
36
Inclusion Criteria

1. Type 2 diabetes according to WHO criteria for over 2 years;

2. VO2peak 60-90% of age-predicted value as measured on a cycle-ergometer;

Exclusion Criteria

1. Use of ß-blocker therapy;

2. Exogenous insulin therapy (for substudy 2 only);

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main study parameters/endpoints: The main study parameter and end-point is the relative improvement in whole-body insulin sensitivity.
Secondary Outcome Measures
NameTimeMethod
Secondary end-points are relative improvements in vascular function parameters using forearm plethysmography, cardiovascular fitness, systemic blood pressure, body composition, lipid metabolism and glycemic control.<br>
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