The effects of exercise based on cadiopulmonary exercise training (CPX) in depression and exploring the mechanisms involved in the effects on PBMC mitochondria of depression - effects of exercise based on CPX in depression

Hokkaido University0 sites15 target enrollmentJanuary 1, 2017

Conditionsmajor depressive disorder, persistent depressive disorder

Overview

Phase: 未知
Intervention: Not specified
Conditions: major depressive disorder, persistent depressive disorder
Sponsor: Hokkaido University
Enrollment: 15
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

We developed an exercise program based on patients' individual level of anaerobic threshold, a submaximal index of aerobic capacity measured by cardiopulmonary exercise testing. We found that in patients diagnosed with major depressive disorder or persistent depressive disorder, our exercise program resulted in a clinically significant reduction in depressive symptoms at week 8, which was maintained at week 16.

Registry

who.int

Start Date

January 1, 2017

End Date

August 1, 2018

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Hokkaido University

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•1\. Patients with severe depression (HAM\-D score 20 or more) 2\. Patients expressing serious suicidal thoughts 3\. Patients with YMRS score 13 or more 4\. Patients with inflammatory disease 5\. Patients with malignant tumor 6\. Patients who can't take exercise using exercise bike due to orthopedic disease 7\. Patients who have usually take exercise at fixed intervals 8\. Patients treated with dialysis for chronic renal failure 9\. patients whom principal investigators consider are not eligible