on-invasive, bedside assessment of systemic endothelial function: a predictor of mortality in intensive care?
Completed
- Conditions
- Systemic endothelial function in critical careHaematological DisordersSystemic endothelial function
- Registration Number
- ISRCTN49531007
- Lead Sponsor
- Royal Victoria Hospital (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
All adult patients admitted to the regional intensive care unit at the Royal Group of Hospitals, Belfast will be eligible for inclusion in the study.
Exclusion Criteria
1. Aged less than 18 years old
2. Pregnancy
3. Inability to achieve radial arterial access
4. Known allergy or sensitivity to salbutamol or glyceryl trinitrate (GTN)
5. Patients transferred from other intensive care units
6. Patients unlikely to survive more than 24 hours
7. Patients with an advance directive regarding limitation of treatment
8. Patients who have a Do Not Attempt Resuscitation (DNAR) order in place
9. Lack of consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intensive Care Unit (ICU) mortality
- Secondary Outcome Measures
Name Time Method 1. Length of ICU stay<br>2. Number of ventilator days<br>3. Incidence of organ failures<br>4. Need for continuous renal replacement therapy <br>5. Duration of inotropic support