Maternal Uterine Artery Doppler Study

Completed

• Conditions: Maternal-Fetal Exchange
• Interventions: Other: Any patient eligible for an Ultrasound greater than or equal to 18 weeks gestation without a fetal or uterine anomaly.

• Registration Number: NCT01698957
• Lead Sponsor: Obstetrix Medical Group

Brief Summary

The purpose of this study is to detect if adding resistance to maternal blood flow from the arm will help increase the blood flow through the uterine arteries to the placenta and the baby.

Detailed Description

In the setting of uteroplacental insufficiency, there is little that can be done to increase blood flow through the uterus and placenta. Historically, women with growth restricted fetuses or oligohydramnios have been placed on bed rest. Unfortunately, this treatment modality has met with only limited success. Cardiologists have long recognized the simple act of making a fist or otherwise occluding blood flow through a limb dramatically increases a person's peripheral vascular resistance. If maternal peripheral resistance can be increased, perhaps the increased differential between the maternal peripheral vascular resistance and that of the uteroplacental unit will increase flow through the uterus and placenta.

Study Timeline

• Study Start: 2012-09
• Study First Submitted: 2012-10-01
• Study First Submitted QC: 2012-10-01
• Study First Posted: 2012-10-03
• Primary Completion: 2016-08
• Study Completion: 2016-09
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-21
• Last Update Posted: 2016-11-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 52

Inclusion Criteria

• Pregnant women greater than or equal to 18 years old
• Able to speak and read English
• Have a singleton pregnancy greater than or equal to 18 weeks gestation

Exclusion Criteria

• Multiple gestation
• Less than 18 weeks gestation
• Uterine anomalies
• Fetal anomalies
• Preeclampsia
• Hypertension
• Inability to have BP cuff on left arm

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
UA Doppler Velocimetry	Any patient eligible for an Ultrasound greater than or equal to 18 weeks gestation without a fetal or uterine anomaly.	Any patient eligible for an Ultrasound greater than or equal to 18 weeks gestation without a fetal or uterine anomaly.

Primary Outcome Measures

Name	Time	Method
Uterine Artery Doppler	at time of routine ultrasound	The purpose of this study is to detect if adding resistance to maternal blood flow from the arm will help increase the blood flow through the uterine arteries to the placenta and the baby.

Trial Locations

Locations (1)

Phoenix Perinatal Associates; 🇺🇸 Phoenix, Arizona, United States