Evaluating the effect of adding dexamethasone to lidocaine in improving the quality of the upper extremity anesthesia through venous injection (Bier's Block) in orthopedic operations
Phase 3
- Conditions
- Intravenous regional anesthesia.Injuries to the wrist and hand AND Injuries to the elbow and forearm(S60-S69)
- Registration Number
- IRCT2016052928158N1
- Lead Sponsor
- Vice chancellor for research, Hormozgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
ASA class I-II, 15 to 65 years old, upper limb injuries distal to the elbow.
Exclusion criteria: Muscle-nerve-skin diseases, allergic reactions, general anesthesia requirement due to inadequate regional anesthesia.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensory block onset. Timepoint: 30 seconds. Method of measurement: Pinprick test (needle 22 gauge bevel).;Sensory block recovery. Timepoint: 30 seconds. Method of measurement: pinprick test (with needle 22 gauge bevel).;Time to first request of analgesic in recovery. Timepoint: 15, 30, 45, and 60 minutes after intervention. Method of measurement: minutes.;Intraoperative opium consumption. Timepoint: 1 hours. Method of measurement: Total fentanyl consumption dose (micro-gram).;Patients satisfaction. Timepoint: 1 hours. Method of measurement: Excellent: if there is no complain during operation. Good: if there is mild discomfort but without the need of analgesia during operation. Moderate: if the patient has discomfort and needs analgesia. Poor: If the patient receives 2 doses of fentanyl (1 microgram/kg) but still has discomfort, and requires sedative doses of propofol (25-75 microgram/kg/min) to tolerate the procedure.
- Secondary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Non-invasive automatic blood pressure monitoring device.;Diastolic blood presure. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Non-invasive automatic blood pressure monitoring device.;Mean arterial blood pressure. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Non-invasive automatic blood pressure monitoring device.;Heart rate. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Beats per minute by an electrocardiographic monitoring device.