Vascular Phenotypes in a Geriatric Populatio
- Conditions
- <p>Memory complaints, microvascular damage, macrovascular damage</p>
- Registration Number
- NL-OMON29291
- Lead Sponsor
- Amsterdam University Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
Age of 65 years or older
-Signed informed consent for the general protocol (METc 2017.148)
Exclusion Criteria
-Insufficient proficiency of the Dutch language.
- Severe cognitive impairment: MMSE score < 16.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are different vascular phenotypes, based on measurements of macro- and microvascular function.</p>
- Secondary Outcome Measures
Name Time Method <p>Secondary study parameters are cognitive functioning, as assessed by neuropsychological assessment, physical performance (handgrip strength, gait speed and Short Physical Performance Battery) and functional outcomes: activities of daily living (ADL) and instrumental ADL (iADL) dependence levels, quality of life, (serious) adverse events and mortality.</p>