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Clinical Trials/NCT03351985
NCT03351985
Unknown
Not Applicable

the Effect of Quantitative Electroencephalogram (qEEG) in Predictive of Post-operation Delirium and Prognosis of Cardiac Surgery Patients

Southeast University, China0 sites56 target enrollmentDecember 1, 2017
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ConditionsDelirium

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Delirium
Sponsor
Southeast University, China
Enrollment
56
Primary Endpoint
amplitude integrated electroencephalogram (aEEG)
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

Delirium is the most common neurological complication of cardiac surgery patients and associated with poor prognosis. In recent years, the important role of quantitative electroencephalogram (qEEG) in brain function monitoring is becoming increasingly prominent. The purpose of this study is to evaluate the effect of qEEG in predictive of post-operation delirium and prognosis of cardiac surgery patients.

Registry
clinicaltrials.gov
Start Date
December 1, 2017
End Date
August 31, 2018
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Southeast University, China
Responsible Party
Principal Investigator
Principal Investigator

Jingyuan,Xu

professor

Southeast University, China

Eligibility Criteria

Inclusion Criteria

  • •The patients of cardiac surgery aged ≥18 years
  • •Signed informed consent

Exclusion Criteria

  • •Patients with a history of any neurologic and psychiatric disease
  • •Cognitive disorder
  • •Stroke history in three years

Outcomes

Primary Outcomes

amplitude integrated electroencephalogram (aEEG)

Time Frame: 24 hours

the electroencephalogram amplitude of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit

Secondary Outcomes

  • alpha frequency band energy(24 hours)
  • beta frequency band energy(24 hours)
  • theta frequency band energy(24 hours)
  • delta frequency band energy(24 hours)
  • alpha variability(24 hours)
  • arterial oxygen saturation (SaO2)(24 hours)
  • central venous oxygen saturation (ScvO2)(24 hours)
  • neuron specific enolase (NSE)(24 hours)
  • interleukin-6 (IL-6)(24 hours)
  • troponin i (TNI)(24 hours)
  • high-sensitivity C-reactive protein (hs-CRP)(24 hours)
  • N-terminal pro brain natriuretic peptide (NT-pro-BNP)(24 hours)

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