Adjunctive Role of Platelets Rich Fibrin in Palatal Wound Healing After Free Gingival Graft Harvesting - Case Series
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 10
- 主要终点
- Pain Assessment by Visual Analog Scale (VAS)
研究概览
简要总结
Free gingival grafts are important to increase zone of attached gingiva and root coverage. This case series reveals role of platelet-rich fibrin (PRF) as adjunctive therapy in palatal wound healing. The superior healing observed at the PRF membrane sites supports its use in accelerating soft-tissue healing. PRF membrane as a palatal bandage is an efficacious approach to protect the raw wound area of a palatal donor site to reduce healing time and patient discomfort.
详细描述
Introduction
Free gingival grafts are one of the common treatment modalities used to increase the zone of keratinized tissue (KT) around implants or prior to ridge augmentation and root coverage. The palatal donor sites had many complications as pain, discomfort and healing by secondary intention. Platelets Rich Fibrin (PRF) is a second generation of platelets concentrate full of growth factors fasten the healing and decrease the pain.
Materials and methods
Ten patients requiring augmentation of KT participated in this case series. The palatal donor sites of 7 of these patients were covered with PRF membranes with a new suturing technique without palatal stent, the other 3 had palatal stent. Palatal tissue will examined clinically after 3, 7, 10 and 14 days. Considerably very fast healing with 0 pain score was observed during one week in the group with PRF.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Systemic free, Good oral hygiene and insufficient attached gingiva prior to ridge augmentation
排除标准
- •High arched palate, medically compromised
结局指标
主要结局
Pain Assessment by Visual Analog Scale (VAS)
时间窗: 1 week postoperative
VAS ranged from 0 (no pain ) to 10 (severe pain)
Clinical healing of the palate
时间窗: 2 weeks postoperative
color match, consistency and thickness of palate (Composite measure)
次要结局
未报告次要终点
研究者
Doaa Adel Salah Khattab
Assistant Lecturer Oral Periodontology Department
Ain Shams University