Soft Tissue Profile Following Socket Preservation With Platelet Rich Fibrin Versus Free Gingival Graft

Not Applicable

• Conditions: Soft Tissue Mass
• Interventions: Other: Free gingival graft; Other: platelet rich fibrin

• Registration Number: NCT03628170
• Lead Sponsor: Cairo University

Brief Summary

Comparing socket preservation with Platelet -Rich Fibrin versus Free gingival graft.

Detailed Description

Extraction of the non restorable tooth, then socket preservation is applied in experimental group using platelet rich fibrin, while in comparative group free gingival graft is applied with socket preservation.

Study Timeline

• Status Verified: 2018-05
• Study First Submitted: 2018-05-04
• Study Start: 2018-06-07
• Study First Submitted QC: 2018-08-09
• Last Update Submitted: 2018-08-09
• Study First Posted: 2018-08-14
• Last Update Posted: 2018-08-14
• Primary Completion: 2019-01
• Study Completion: 2019-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• Age range 25-50 years.
• Non- restorable teeth indicated for extraction.
• Good oral hygiene.
• Intact facial and lingual plates of bone, without infection or pathosis.
• Adequate apiacl bone for primaru stability

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Exclusion Criteria

• Presence of uncontrolled Systemic disease eg: diabetes, bone disease or the use of medicines that interfere with bone metabolism, history of head and neck radiotherapy.
• Presence of periodontal and/or periapical infection.
• Smokers.
• Non-compliant patients.
• Pregnancy or lactation in females.
• History of head and neck radiotherapy.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Free gingival graft group	Free gingival graft	Extraction of the tooth followed by using free gingival graft to cover the socket for socket preservation.
PRF (Platelet -rich fibrin) group	platelet rich fibrin	Extraction of the tooth followed by Platelet rich fibrin placed in the socket covered bu platelet rich fibrin membrane for socket preservation.

Primary Outcome Measures

Name	Time	Method
Soft tissue profile change	6 months	Optical scanning by optical scanner at baseline to the preoperative cast of the related area, then optical scanning to postoperative cast of the surgical area after 6 months. Then, superimposition between the two scans of the casts will be performed to measure the difference or change in the amount of soft tissue profile measured in millimeters between baseline and at 6 months

Secondary Outcome Measures

Name	Time	Method
Crestal bone level change	6 months	measured by Cone beam computed tomography (CBCT) taking the neighboring teeth as reference points, with superimposition between readings at baseline and at 6 months.; Superimposition will identify the difference or change in crestal bone level measured in millimeters between baseline and at 6 months.

Trial Locations

Locations (1)

Faculty of Oral and dental medicine, Cairo University; 🇪🇬 Cairo, Egypt