Comparison of the effect of two drug combinations: Etomidate-Sufentanil with Ketamine-Sufentanil-Midazolam during laryngoscopy
Phase 3
Recruiting
- Conditions
- patients who need general anesthesia with tracheal intubation.
- Registration Number
- IRCT20090129001615N4
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
Patients with ASA (American Society of Anesthesiologists) grade:1 or 2
Patients aged 18 to 65 years
Patients who need tracheal intubation and general anesthesia
Exclusion Criteria
Patients with heart failure disease
Patients who are addicted to drugs
Patients with airway anomalies
Patients with hepatic failure disease
Patients with renal failure disease
Patients with over 65 years or under 18 years
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure mean in each group. Timepoint: Before intervention and 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Blood pressure manometer.;Diastolic blood pressure mean in each group. Timepoint: Before intervention and 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Blood pressure manometer.;Heart rate mean in each group. Timepoint: Before intervention and 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Heart monitoring device.
- Secondary Outcome Measures
Name Time Method Arterial oxygen saturation mean in each group. Timepoint: Before intervention and 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Pulse oximeter.;Electrocardiogram ST-T changes relative frequency in each group. Timepoint: Before intervention and 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Electrocardiogram.