?Effects of adenosine in controlled reperfusion after heart valvular surgery

Phase 3

• Conditions: Surgery of the valvular heart disease.; Chronic rheumatic heart diseases, Congenital malformations of the circulatory system; I05-I09, Q

• Registration Number: IRCT20211225053519N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Elective (not emergency) valvular surgery
Cardiopulmonary bypass, and need for aortic cross-clamp and cardioplegia during operation
Ejection fraction more than 35% before the surgery
Negative history for previous cardiac surgery
Lack of ventricular hypertrophy based on the preoperative echocardiography
Lack of Inotropic consumption before the operation
Lack of pacemakers or implantable cardioverter-defibrillator
Pulmonary artery pressure less than 65mm Hg
Filling the informed consent form

Exclusion Criteria

Returning to cardiopulmonary bypass during the operation
Need for intra aortic balloon pump
Need for mechanical heart support

Study & Design

• Study Type: interventional
• Study Design: Not specified