A clinical research to study the root resorption by estimating the levels of biomarker in the saliva and X- ray in patients undergoing fixed orthodontic therapy after injection of blood component(i-PRF) to fasten the orthodontic tooth movement.
Not Applicable
- Conditions
- Health Condition 1: K002- Abnormalities of size and form ofteeth
- Registration Number
- CTRI/2023/08/056931
- Lead Sponsor
- Dr JN Rupa
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
patient with Class I / half cusp Class II malocclusion cases with moderate to severe crowding in maxillary arch ( >6mm Little’s Irregularity Index).No previously reported or observed active orthodontic treatment. Completed root apexification assessed with periapical radiographs. Patients with healthy periodontium and no gingival inflammation at the experimental sites. Patients with positive informed consent.
Exclusion Criteria
patient with Platelet count less than normal 150000 per µl of blood. Patients on regular antibiotics, steroids or anti-inflammatory drugs. Signs of external apical root shortening observed at the preoperative radiographic examination.
Non- compliant patient with poor oral hygiene.
Syndromic patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Estimate and compare levels of DSPP in GCF at different interval of time during alignment of maxillary incisors with and without i-PRF injection.Timepoint: preoperative, before anterior alignment, 4 weeks, 8 weeks,3 month, 4 month, 6 month
- Secondary Outcome Measures
Name Time Method 1.To estimate the amount and extent of root resorption in the maxillary incisors after alignment with and without i-PRF injection using CBCT.Timepoint: preoperative and postoperative