Entropy guided sevoflurane administration and end Oxygenator sevoflurane concentration in Cardiopulmonary bypass surgery
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/11/059847
- Lead Sponsor
- Armed Forces Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients undergoing elective on pump cardiopulmonary bypass surgery
2.Written and informed consent
Exclusion Criteria
1. An active infection of temperature > 38 degrees centigrade
2. History of a neurological disease
3. Previously diagnosed Renal and Hepatic disorder
4. Emergency surgery
5. Any kind of diagnosed or suspected syndrome
6. Deep Hypothermic circulatory arrest
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in sevoflurane end oxygenator concentration with entropy guided sevoflurane administrationTimepoint: At the time of induction <br/ ><br>At the time of skin incision <br/ ><br>At the time of sternotomy <br/ ><br>At the time of starting of CPB <br/ ><br>At the time of Cross clamping of Aorta <br/ ><br>At 10min intervals during CPB <br/ ><br>At the time of removal of Cross clamp from Aorta <br/ ><br>At the time of stopping of CPB <br/ ><br>At the time of skin Closure
- Secondary Outcome Measures
Name Time Method IBP <br/ ><br>MAP <br/ ><br>CPB FLOW <br/ ><br>SEVOFLURANE Dial Concentration (%w/v) <br/ ><br>Body Temperature <br/ ><br>ETCO2 <br/ ><br>FiO2 <br/ ><br>VISTimepoint: AT 10 min intervals during CPB