Improving gait initiation after stroke

Not Applicable

• Conditions: stroke; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation; Stroke - Ischaemic; Stroke - Haemorrhagic

• Registration Number: ACTRN12611000915954
• Lead Sponsor: Dr James Stinear

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-08-26
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

First ever ischemic or haemorrhagic stroke between 6 months and 5 years prior to enrolment; the ability to initiate gait without assistive devices such as walking sticks, handrails; a Fugl-Meyer Lower Limb score between 15 and 30 (out of 34); paretic ankle dorsiflexion of > 10 degrees; the ability to follow instructions; and the ability to give informed consent.
Except for age (>45 years), there are no specific inclusion criteria for healthy subjects.

Exclusion Criteria

Brainstem or cerebellar infarction; other neurological or medical disorders that would prevent participation in the study; contraindications to TMS or MRI; and medications that are known to alter motor system excitability.
Healthy subjects will be excluded if they have any neurological disorders; orthopaedic conditions that might affect gait; contraindications to TMS; and medications that are known to alter motor system excitability.

Study & Design

• Study Type: Interventional
• Study Design: Not specified