COVID@Home: cardiovascular disease and risk in non-hospitalized Covid-19 patients

Completed

Conditions: COVID@Home
10028593

Registration Number: NL-OMON51240

Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 100

Inclusion Criteria

Participants of the Rotterdam Study who recovered from a Covid-19 infection at
home.

Exclusion Criteria

Participants with prior known myocardial infarction (based on the information
previously collected within the Rotterdam Study from the GP registries) and/or
eGFR < 30 ml/min (based on the results acquired in previous rounds of the
Rotterdam Study), will be excluded from this study.

Subjects who meets any of the following criteria will be excluded from
undergoing the CMR: *
- Known contra-indications for CMR (e.g.: severe claustrophobia, metal
implants, severe renal failure)
- (e)GFR < 30 ml/min
- Known allergy for contrast

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cardiac MRI parameters</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Parameters for cardiac structure en function.<br /><br><br /><br>Also:<br /><br>- Blood makers, including lipids (total cholesterol, HDL-cholesterol and<br /><br>triglycerides), glucose, CRP, Creatinine, Troponin I or T, NT-proBNP)<br /><br>- Data collected from questionnaires, e.g. covid-related symptoms and fatigue<br /><br>- Cardiovascular risk factors<br /><br><br /><br>Other study parameters:<br /><br><br /><br>Sleep and activity:<br /><br>- Sleep (Total sleep time, Sleep onset latency, Wake after sleep onset, Sleep<br /><br>efficiency)<br /><br>- 24-hour activity rhythms (Interdaily stability, Intradaily variability, Onset<br /><br>lowest hours of activity)<br /><br>- Mental health</p><br>