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临床试验/NCT03069391
NCT03069391Unknown不适用

The Interactive Physical and Cognitive Exercise System (iPACES™): A Neuro-exergame for Preventing Alzheimer's and Ameliorating Cognitive Impairment

Union College, New York2 个研究点 分布在 1 个国家目标入组 31 人开始时间: 2017年3月4日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
31
试验地点
2
主要终点
executive function composite score

研究概览

简要总结

This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise. In particular, this study will investigate the possible benefits of physical exercise (such as pedaling an under-table stationary elliptical) or mental exercise (such as playing a videogame on a portable tablet), or combining these activities together (as in the iPACES™ exergame).

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • co-residing older adults (e.g., spouses, partners, roommates, relatives)
  • both at least 50 years of age
  • normative/typical cognitive function or those with Mild Cognitive Impairment (MCI) or mild Neurocognitive Disorder (mNCD) or early Alzheimer's disease
  • adequate vision and dexterity for on-screen assessments
  • able to pedal an under-table elliptical
  • permission of primary care provider and cardiologist (if applicable)

排除标准

  • history of seizure
  • Parkinson's disease
  • significant dementia/memory loss

结局指标

主要结局

executive function composite score

时间窗: change over time from baseline to 3 months

comprised of scores from Stroop, Trails, and Flanker

次要结局

  • Sit-Stand Test(change over time in score from baseline to 3 months)
  • brain-derived neurotrophic factor (BDNF)(change over time from baseline to 3 months)

研究者

发起方
Union College, New York
申办方类型
Other
责任方
Principal Investigator
主要研究者

Cay Anderson-Hanley, PhD

Associate Professor

Union College, New York

研究点 (2)

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