NL-OMON33838RecruitingNot Applicable
Adipose tissue depot-specific differences in adipocyte function and inflammatory mediators in patients with type 2 diabetes mellitus and cardiovascular disease - Adipose tissue characteristics in patients with T2DM and in CVD
niversitair Medisch Centrum Sint Radboud0 sites45 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 45
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •Control subjects (males and females): Age: 40-60 yrs, BMI: 25-30 kg/m2, plasma glucose < 6.1mM ;Type 2 diabetes mellitus (T2DM) patients (males and females): subjects diagnosed with the disease T2DM, age: 40-60 yrs, BMI: 25-30 kg/m2;Subjects suffering cardiovascular disease (males and females): subjects diagnosed with peripheral vascular disease, history of myocardial infarction, angina pectoris, age: 40-60 yrs, BMI: 25-30 kg/m2
Exclusion Criteria
- •Control group: presence of a chronic or acute inflammation and/or autoimmune disorder, insulin resistance;Type 2 diabetes mellitus (T2DM) patients: presence of a chronic or acute inflammation and/or another autoimmune disorder ;Subjects suffering cardiovascular disease: presence of another chronic or acute inflammation and/or autoimmune disorder, insulin resistance
Investigators
Similar Trials
Not yet recruiting
Phase 1
Evaluation the effect of conditioned media of adipose drived stem cells on acne scaratrophic scar.Scar conditions and fibrosis of skinL90.5IRCT20080901001159N33Tehran University of Medical Sciences30
Recruiting
Phase 1
Evaluation of the effect of SVF cells and nanofat for autologous fibroblast function in facial rejuvenatioIRCT20200127046282N30Tehran University of Medical Sciences10
Completed
Phase 2
A comparative study between adipocyte-derived mesenchymal stem cell versus intra-articular hyaluronic acid interventions in early osteoarthritis: Prospective Randomized Open, Blinded End-pointPatients with symptomatic knee osteoarthritis at Kellgren &Lawrence stage IIAdipocyte-derived mesenchymal stem cellsStem cell therapyRegenerative medicineKnee osteoarthritisTCTR20230929002ational Research Council of Thailand (NRCT)44
Active, not recruiting
Phase 1
Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes: A Randomized Open Intervention Study That Compares Empagliflozin, Pioglitazone and Semaglutide (DiaSpax)Diabetes type 2MedDRA version: 20.0Level: SOCClassification code: 10027433Term: Metabolism and nutrition disorders Class: 6MedDRA version: 21.1Level: LLTClassification code: 10045242Term: Type II diabetes mellitus Class: 10027433MedDRA version: 20.0Level: PTClassification code: 10012601Term: Diabetes mellitus Class: 100000004861CTIS2024-513416-98-00Karolinska University Hospital60
Completed
Not Applicable
Adipose tissue in overweight individuals with and without the metabolic syndrome; differences in free fatty acid profile in Fasting and Fed state using 1H-MR-spectroscopy.adipose tissue dysfunctionoverweight1001842410003216NL-OMON39951niversitair Medisch Centrum Utrecht30