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临床试验/NCT05082792
NCT05082792Unknown不适用

The Role of Doppler Ultrasound in Assessment of Local Factors Affecting Maturation of Arteriovenous Fistula in Hemodialysis Patient

Sohag University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2021年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
50
试验地点
1
主要终点
maturation of AVF

研究概览

简要总结

the long term survival of the chronic kidney disease (CKD) patients depends on the adequacy of dialysis via good vascular access. the arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis. pre-operative evaluation and periodic monitoring of the AVF after creation with well-defined applied criteria by color doppler ultrasound (CDUS) will help to reduce rate of access failure and achieve better cumulative patency rate of fistulas.

详细描述

In recent years, the improvement in the diagnosis and treatment of chronic kidney disease (CKD) has led to increase the number of patients who need hemodialysis, adequacy of which depends upon the appropriately placed vascular access. Although the arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis, there is still a high rate of failure to mature in clinical practice. To increase the use of AVFs, especially in the co-morbid patients, a thorough pre-operative evaluation and periodic monitoring after AVF creation by color doppler ultrasound (CDUS) allows placement of AVF in higher proportion of patients, and early detection of access dysfunction with subsequent intervention that reduce the rate of access failure.

Doppler ultrasound is the main imaging modality for assessment of dialysis access circuits as its gives information on the morphological criteria and evaluates the inflow and outflow flows. CDUS is non-invasive modality, of low cost, not using ionizing radiation or iodinated contrast media.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
15 Years 至 80 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •CKD and ESRD patients on hemodialysis, in whom native arteriovenous fistula operation is needed
  • •both sexes are included.
  • •age group from 15-80years
  • •upper limb arteriovenous fistula only.
  • •native arteriovenous fistula.
  • •surgically succeeded AVF

排除标准

  • •we will exclude:
  • •patients refused to be in the research.
  • •Patients with AVF not in the upper limbs.
  • •Patient of age less than 15years and above 80years.
  • •patients with synthetic grafts.

研究组 & 干预措施

doppler US for native AVF in upper limb

Other

creation of native arteriovenous fistula in upper limb in chronic kidney disease patients on hemodialysis

干预措施: doppler ultrasound (Diagnostic Test)

结局指标

主要结局

maturation of AVF

时间窗: 6 months

maturation is considered successful if the fistula patent has a diameter \>6mm, located \<6mm maximum depth from skin surface, with PSV 400cm/s, flow volume 600ml/min, within 6 weeks post-surgery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Areej Mahmoud Ibrahim

Resident doctor at diagnostic and interventional radiology department Sohag University Hospitals

Sohag University

研究点 (1)

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