Pilot-study; Investigation on the application of a new surgical technique (DMET) for treatment of Fuchs endothelial dystrophy

Completed

• Conditions: Fuchs endothelial dystrophy / corneal weakness; 10015919; 10015957

• Registration Number: NL-OMON44087
• Lead Sponsor: IIOS

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

Patients suffering from Fuchs endothelial dystrophy with no cells left in the center of the cornea, but still possessing cells at the periphery of the cornea.

Exclusion Criteria

When no endothelial cells are present in the peripheral part of the cornea

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- visual acuity --> measured by the optometrist using a Snellen chart (standard<br /><br>procedure)<br /><br>- Pachymetry of the cornea --> measured using a pentacam apparatus and an<br /><br>Anterior Segment Optical Coherence Tomography apparatus (OCT) (standard<br /><br>procedures)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Density of endothelial cells postoperative --> measured using a non-contact<br /><br>specular microscope (standard procedure)</p><br>