The prospective study on differentiation and treatment of membranous nephropathy by Wenyang Huaji method
- Conditions
- Membranous Nephropathy
- Registration Number
- ITMCTR2100004443
- Lead Sponsor
- Beijing Hospital of TCM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1.Conforms to the MN diagnostic criteria.
2.Conforms to the diagnostic criteria of Shaoyin Taiyin syndrome.
3.The patient has signed the informed consent.
4.Between the ages of 18 and 75.
5.CKD stage I-III, eGFR > 30ml/min, serum albumin > 15g/L.
1. Progressive membranous nephropathy (progressive decrease of renal function;Kidney biopsy showed necrotizing capillaritis and > 50% large crescent), accompanied by IgA nephropathy, diabetic nephropathy and other kidney diseases.
2. Confirmed by hepatitis B, systemic lupus erythematosus, tumor, drug damage and other factors secondary and need to actively treat the primary disease, such as active hepatitis B and persistent liver function test transaminase abnormalities, or anti-nuclear antibodies, double Abnormal strand DNA, ANCA or other indicators of immune disease.
3. With acute central nervous system disease, severe gastrointestinal disease, a history of HIV infection, a history of mental illness or a history of malignancy.
4. With other organ diseases and dysfunction, and with life-threatening complications such as severely infected persons.
5. Pregnant or lactating women.
6. Other clinical trials are under study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24-hour urine protein;serum albumin;
- Secondary Outcome Measures
Name Time Method Anti-PLA2R Antibody;Total Cholesterol;TCM syndrome scores;Triglyceride;