The relationship between visual hallucinations, visual perception and attention in patients with schizophrenia

Completed

• Conditions: non-affective psychotic disorder; psychosis; 10039628

• Registration Number: NL-OMON45154
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 51

Inclusion Criteria

For patients:
1) meeting DSM-IV criteria for schizophrenia, schizophreniform disorder, schizoaffective disorder or psychotic disorder NOS;
2) in case of psychiatric comorbidity, the schizophrenia spectrum disorder is predominating;
3) age between 18-55;
4) speaking Dutch fluently;
5) being able to give informed consent.;Healthy controls must fulfill the following criteria:
1) age between 18-55;
2) speaking Dutch fluently;
3) being able to give informed consent.

Exclusion Criteria

1) other psychiatric disorders than above mentioned schizophrenia spectrum disorders; that presumably affect our data;
2) the presence of accompanying neurological disorders that supposedly influence our data;
3) visually acuity less than 50 percent (Snellen chart);
4) visually field defects (Donders technique);
5) cognitive impairment, which is assessed by Mini-Mental State Examination. The cut-off point is <26.
Exclusion criteria fMRI:
6) presence of implantable devices (electronically, magnetically or mechanically activated, for example implanted insuline pumps, cardiac pacemakers, cardioverter-defibrillators, metallic prosthetic heart valves, cochlear implants);
7) medical disorders because of which patient are unable to lie flat for about 30 minutes, for example poorly controlled heart failure and poorly controlled or severe respiratory disease;
8) ferromagnetic clips;
9) intraocular metallic bodies;
10) pregnancy;
11) claustrophobia;
12) colored tattoos;
13) coils (exception: Mirena);
14) weighing more than 140 kg.;Furthermore, healthy controls are being excluded if they ever have had a psychotic episode; or experience VH (besides due to severe sleep deprivation or use of medication/alcohol/drugs), or if they have a first degree family member who had a psychotic episode or has a psychotic disorder.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified