mbilical cord blood collected from term babies for transfusion in premature babies
Phase 3
- Conditions
- Health Condition 1: D648- Other specified anemias
- Registration Number
- CTRI/2019/11/021886
- Lead Sponsor
- Intramural GATE Research fund from SRIHER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. For collection of UCB - Term (>=37 weeks gestation) infants delivered by elective caesarean section
2. For transfusion of UCB - Premature infants <1500 g birth weight requiring transfusion during the NICU stay
Exclusion Criteria
For collection of UCB
1. Mothers positive for HIV, HBsAg, HCV or VDRL
2. Mothers positive for unusual RBC antibodies screen
3. Mother who opt for cord blood banking
4. Maternal-fetal iso-immunization
5. Lack of consent
For transfusion of UCB
1. UCB compatible with babyâ??s blood not available
2. Lack of consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of red cell concentrates (RCC) transfusions in preterm infants that are covered by UCBTimepoint: Until discharge from the NIC
- Secondary Outcome Measures
Name Time Method 1. Success rate of UCB collection after DCC (defined as absolute UCB volume â?¥ 25 mL) <br/ ><br>2. Volume of UCB collected/volume of RCC obtained <br/ ><br>3. Proportion of UCB units with satisfactory quality based on microbiological, hematological <br/ ><br>and biochemical parameters available until 21 days of storage.Timepoint: 21 days of storage (maximum)