THE COMPARISON OF POST OPERATIVE RECOVERY AND OUTCOME OF TOTAL HIP REPLACEMENT SURGERY, WHEN PERFORMED BY DIRECT ANTERIOR APPROACH IN COMPARISON WITH POSTERIOR APPROACH

Phase 3

Completed

• Conditions: Osteoarthritis of hip, unspecified,

• Registration Number: CTRI/2024/01/062034
• Lead Sponsor: AIIMS NEW DELHI

Brief Summary

The study aims to compare the clinical and radiological outcomes in patients undergoing Total Hip Arthroplasty (THA) with direct anterior approach (DAA) versus posterior approach. Blood tests, MRI, EOS scan, Gait analysis, Radiological and clinical evaluation shall be done at preoperative period, immediate postop period, and at 2 weeks, 6 weeks, 3 months and 1 year postoperatively.  Primary objectives being:

• To compare tissue damage between Direct Anterior Approach (DAA) versus Posterior Approach THA by blood tests and MRI.

• To compare functional outcomes between DAA vs Posterior approach THA using patient reported outcome scores and Gait analysis.

• To compare rate of return to activities of daily living using a milestone diary.

• To compare the radiological outcomes between the two groups for optimal implant positioning and leg length using standard radiographs and EOSTM scan.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-03-09
• Study Start: 2024-05-02

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Adult patients aged between 18-70 years with unilateral symptomatic hip arthritis undergoing unilateral cementless THA.

Exclusion Criteria

• Patients with previous prosthetic hip replacement devices/ revision surgeries.
• Patients aged less than 18 years or more than 70 years.
• Patients with the presence of infections- highly communicable diseases like AIDS, venereal diseases, hepatitis, pulmonary tuberculosis.
• Patients undergoing simultaneous hip and knee arthroplasty.
• Patients not giving consent.
• Patients with Crowe 3 and 4 hip dysplasias.
• Patients with neuromuscular disorders or musculoskeletal disorders or diseases that may adversely affect normal weight bearing or gait 9.
• Patients with active major psychiatric illness or active metastatic disease.
• Patients with spinopelvic involvement and difference in sacral slope in standing and sitting lateral spine x ray less than 10º.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the clinical and radiological outcomes of THA with direct anterior approach	Preoperative period upto 1 year of Postoperative follow up, including regular follow ups at 2 weeks, 6 weeks, 3 months and 1 year.
(DAA) versus posterior approach.	Preoperative period upto 1 year of Postoperative follow up, including regular follow ups at 2 weeks, 6 weeks, 3 months and 1 year.

Secondary Outcome Measures

Name	Time	Method
• To compare tissue damage between Direct Anterior Approach (DAA) versus Posterior Approach THA by blood tests and MRI.	• To compare functional outcomes between DAA vs Posterior approach THA using patient reported outcome scores and Gait analysis.

Trial Locations

Locations (1)

AIIMS, New Delhi; 🇮🇳 Delhi, DELHI, India

AIIMS, New Delhi

🇮🇳Delhi, DELHI, India

Dr Arjun C

Principal investigator

9986771186

mailtoarjun.c@gmail.com