EUCTR2011-006090-25-EE进行中（未招募）不适用
The Impact of Heart Rate on Central Hemodynamics of Antihypertensive Therapy
Tartu Ülikooli kardioloogiakliinik0 个研究点开始时间: 2011年12月29日最近更新:
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Age 18-75 years
- •Dual chamber (atrium and ventricle) cardiac pacemaker placed due to sick sinus syndrome (at least 1 month after implantation)
- •Good atrioventricular conductance (PQ interval < 250 msec)
- •Study subject has signed the informed consent form
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 30
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 70
排除标准
- •Patients with contraindication or intolerance to beta-blockers, ivabradine, or their adjuvants
- •Use of antiarrythmic drugs (sotalol, amiodarone, propafenone)
- •History of several episodes of atrial fibrillation
- •Use of antibiotics
- •Acute or chronic inflammatory diseases
- •Resting blood pressure < 110/70 mmHg
- •Atrioventricular conductance disorders (patient needs permanent pacing)
- •Long QT interval on resting ECG
- •Severe liver or kidney disorder
- •Pregnant or breast-feeding women
- •Women of child-bearing potential not using contraception
- •Previous myocardial infarction or stroke
- •Current stable angina pectoris
- •Total cardiovascular risk higher than moderate-high (in first phase)
- •No insurance provided by Estonian Health Insurance Fund
研究者
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