Cognition Following Computer Assisted Total Knee Arthroplasty: A Prospective Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cognition
- Sponsor
- Rothman Institute Orthopaedics
- Enrollment
- 100
- Primary Endpoint
- Folstein Mini Mental State Examination (MMSE)
- Status
- Completed
- Last Updated
- 17 years ago
Overview
Brief Summary
A significant number of patients experience postoperative cognitive changes following total joint arthroplasty. Among other causes, the mental status change may be the result of fat and bone marrow debris embolization. We hypothesized that the use of computer assisted total knee arthroplasty, which does not utilize intramedullary alignment rods, would produce less fat and bone marrow debris embolization and, hence, fewer mental status changes.
Detailed Description
Inclusion criteria * Primary, cemented knee arthroplasty * Unilateral or bilateral TKA Exclusion criteria * Patient is unable to speak English * Unable to read and write * Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.) * Patients with history of IV drug abuse * Previous history of dementia * Patients on mental status changing medications
Investigators
Eligibility Criteria
Inclusion Criteria
- •Primary, cemented knee arthroplasty
- •Unilateral or bilateral TKA
Exclusion Criteria
- •Patient is unable to speak English
- •Unable to read and write
- •Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.)
- •Patients with history of IV drug abuse
- •Previous history of dementia
- •Patients on mental status changing medications
Outcomes
Primary Outcomes
Folstein Mini Mental State Examination (MMSE)
Time Frame: 6 Months Post-Operative