Genomic based risk stratification in prostate cancer screening.

Completed

• Conditions: prostate cancer; Prostate carcinoma; 10038597; 10036958

• Registration Number: NL-OMON37676
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15000

Inclusion Criteria

- Men randomised to the screening arm of ERSPC Rotterdam
- Signed informed consent

Exclusion Criteria

None

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>SNPs profiling of 110 known SNPs and relate those to the available follow-up<br /><br>data containing information of prostate cancer detection, treatment,<br /><br>progression and casus specific death.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Assess the possibilities to enhance existing risk stratification tools with<br /><br>genomic based information.</p><br>