Train the sedentary brain: move smart. The cognitive benefits of an interactive cycling training in APOEe4 carriers and non-carriers in early stage dementia
Completed
- Conditions
- Dementia, Alzheimer, Cognitive decline, Physical activity
- Registration Number
- NL-OMON29449
- Lead Sponsor
- Radboudumc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 171
Inclusion Criteria
Age > 60 years; diagnosis of dementia; Mini Mental State Examination score higher than 20; having insufficient physical activity according to the ACSM guideline for older adults, maximum of 30 minutes five days a week moderate intensity
Exclusion Criteria
Wheelchair bound, use of dementia targeted nutritional supplements (e.g. Souvenaird) within the last three months, severe cardiovascular problems that limit physical activity, brain trauma, epilepsy, progressive or terminal disease, severe depression, history of alcoholism, severe visual problems, severe auditory problems, problems with the Dutch language and mental incompetence
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Executive functioning (set-shifting, response inhibition)
- Secondary Outcome Measures
Name Time Method Verbal and visual-spatial memory, working memory, attention, psychomotor speed, physical fitness, levels of physical activity, quality of life. <br>Frailty (Evaluative Frailty Index for Physical Activity)