Comparing Efficacy of Hydrodissection With Hyaluronic Acid vs 5% Dextrose for Carpal Tunnel Syndrome: A Randomized Controlled Trial and Ultrasonographic Evaluation of Median Nerve Gliding
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Boston CTS (carpal tunnel syndrome) questionnaire
研究概览
简要总结
Compare the efficacy on carpal tunnel syndrome (CTS) treatment between hydrodissection with hyaluronic acid (HA) vs 5% dextrose
详细描述
Compare the efficacy on carpal tunnel syndrome treatment between hydrodissection with hyaluronic acid vs 5% dextrose through ultrasonographic evaluation.; 2) Evaluate the association of median nerve gliding results between using duplex Doppler ultrasound and B mode video with cross-correlation algorithm.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
盲法说明
Hyaluronic acid and dextrose are both transparent, which is prepare by technician who is not participate in intervention and assessment
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •20-80 years old patients with carpal tunnel syndrome
排除标准
- •pregnancy, Diabetes, hypothyroidism, uremia, rheumatoid arthritis, coagulopathy, cervical radiculopathy and patients who has ever received surgery for carpal tunnel syndrome or wrist fracture
结局指标
主要结局
Boston CTS (carpal tunnel syndrome) questionnaire
时间窗: before injection , 2 weeks, 3 months and 6 months after injection.
The Boston CTS questionnaire is self-administered and is composed of two parts: the symptom severity scale (11 questions) and the functional status scale (8 questions).A final score is calculated for each scale (the sum of the individual scores divided by the number of items) and ranges from 1 to 5, with a higher score indicating a more severe handicap.
次要结局
- Ultrasonography (B mode) of median nerve(before injection , 2 weeks, 3 months and 6 months after injection.)
- Nerve conduction study (NCS) of median nerve(before injection , 3 months and 6 months after injection.)
- Ultrasonography (duplex Doppler) of median nerve(before injection , 2 weeks, 3 months and 6 months after injection.)