The Efficacy Of percutaneous coronary intervention (PCI) on diastolic function in patients with coronary artery disease.

Early Phase 1

Conditions: Heart diastolic dysfunction.
Other forms of heart disease
I30-I52

Registration Number: IRCT201111238182N1

Lead Sponsor: Vice chancellor for research, Kermanshah university of medical sciences and health services

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 51

Inclusion Criteria

Pre PCI known CAD patients with any degree of diastolic dysfunction (grade 1 to 4) and LVEF>30% by echocardiography.
Exclusion criteria: left ventricular hypertrophy (LVH) , uncontrolled hypertension (resting blood pressure>140/90 mm hg), Atrial fibrillation rhythm, hypertrophic cardiomyopathy, elevated Cr level, bundle branch or complete heart block, severe ventricular arrhythmias, severe valvular heart diseases, cardiac pacemakers and prior coronary artery bypass graft surgery

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Grade of diastolic dysfunction. Timepoint: before and three months after PCI. Method of measurement: By echocardiography.;DT. Timepoint: Before and three months after PCI. Method of measurement: By echocardiography.;IVRT. Timepoint: Before and three months after PCI. Method of measurement: By echocardiography.;E/A. Timepoint: Before and three months after PCI. Method of measurement: By echocardiography.;Mitral A duration /PVa duration. Timepoint: Before and three months after PCI. Method of measurement: By echocardiography.;PVs/PVd. Timepoint: Before and three months after PCI. Method of measurement: By echocardiography.;E/Ea. Timepoint: Before and three months after PCI. Method of measurement: By echocardiography.

Secondary Outcome Measures