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Effect of levobupivacaine infiltration versus placebo on perineal postpartum pain in episiotomy of primiparous, after instrumental delivery.

Phase 1
Conditions
Episiotomy (inclusion of primiparous patients giving birth by instrumental delivery -Suzor forceps, vacuum extraction, Thierry spatulas with episiotomy).
Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
Registration Number
EUCTR2015-005247-14-BE
Lead Sponsor
Centre Hospitalier Universitaire Brugmann
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Female
Target Recruitment
330
Inclusion Criteria

-Primiparous
-Vaginal delivery with instrumentation (Suzor forceps, vacuum extraction, Thierry spatulas), with episiotomy
-Fœtus In cephalic position
-Single pregnancy
-Patient at least 18 years old
-Term superior or equal to 37 weeks of amenorrhea
-Patient under epidural analgesia
-Patient affiliated to a social security scheme
-Patient having a good understanding of French
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 330
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

-Ineffective epidural analgesia, defined as the need of an additional local anesthesia for episiotomy repair
- Perineal tear of 3rd and 4rd grade, according to the Anglo-saxon classification
- Contra-indication to levobupivacaine, paracetamol, ketoprofen
- Protocol participation refusal
- Postpartum hemorrhage requiring arterial embolization, reoperation (evacuation of a vaginal thrombus, vessel ligation, hysterectomy by laparotomy) or balloon Bakri® placement.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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