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Baseline Cardiovascular Measurements in Pediatric Spinal Cord Injury

Completed
Conditions
Spinal Cord Injury
Registration Number
NCT01599455
Lead Sponsor
Shriners Hospitals for Children
Brief Summary

Following spinal cord injury (SCI), the body loses normal control of blood pressure and heart rate, and there is a risk of sudden and dangerous increases in blood pressure, namely, autonomic dysreflexia (AD). It is important to be aware of baseline blood pressures and heart rates in individuals in order to detect AD. However, baseline values vary in developing children, and may be more variable in children with SCI. Thus, the objective of this study is to determine baseline blood pressure and heart rate measurements in children with SCI during rest and during urodynamic testing.

The investigators hypothesize that 1) blood pressures will increase with increasing age and body mass index; 2) heart rate will decrease with increasing age; 3) blood pressures will increase with increase in bladder filling; 4) blood pressures will increase will increase with increasing duration of injury.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
146
Inclusion Criteria
  • children and adolescents with spinal cord injury
  • age 18 years or younger
Exclusion Criteria
  • known history of hypertension, cardiac, renal, or thyroid disease
  • recent surgical procedure less than 2 weeks prior to admission or visit
  • fever or signs of active infection or inflammation

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood pressure readingsat regularly scheduled medical appointments
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Shriners Hospitals for Children - Chicago

🇺🇸

Chicago, Illinois, United States

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