Comparison of preoperative nebulisation with Magnesium Sulphate and ketamine for prevention of postoperative Sore Throat After Endotracheal Intubation in a Tertiary care Centre
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To compare the efficacy of ketamine nebulisation and magnesium sulphate nebulisation to decrease incidence of postoperative sore throat in patients undergoing endotracheal intubation
研究概览
简要总结
Modern Anaesthesia is safe, balanced and of utmost importance to improve surgical
outcome
So it is essential to decrease the incidence and severity of anaesthesia related complications. The incidence of post operative sore throat is about 21-65%. It is still a major
complaint as there are various causative factors of post operative sore throat like erosion and inflammation due to endotracheal intubation, mucosal trauma, lack of airway humidity, suctioning of airway. So, all efforts are made to decrease post operative sore throat in patients undergoing general anaesthesia with endotracheal intubation.
There are various non pharmacological and pharmacological methods used to decrease post operative sore throat. Non pharmacological methods include smaller size endotracheal tube, lubrication of endotracheal tube with water-soluble jelly, careful airway instrumentation, intubation after full relaxation, pharyngeal and oral suction, minimal intracuff pressure and extubation after fully deflating tracheal cuff. Pharmacological methods to decrease post operative sore throat includes inhalation of steroids like beclomethasone and fluticasone, gargling with azuline sulphate, aspirin, ketamine, nebulization with magnesium sulphate, ketamine, lignocaine and intracuff administration of alkalized lignocaine
The study is conducted to compare the incidence of post operative sore throat using ketamine and magnesium sulfate nebulization in patients who will be undergoing endotracheal intubation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1.ASA 1 and 2 2.General anaesthesia requiring Endotracheal intubation 3.Informed consent.
排除标准
- •Existing sore throat Hypersensitivy to study drug Oral surgeries BMI greater than 30 Pregnant and lactating women Patients with upper respiratory tract symptoms.
结局指标
主要结局
To compare the efficacy of ketamine nebulisation and magnesium sulphate nebulisation to decrease incidence of postoperative sore throat in patients undergoing endotracheal intubation
时间窗: Baseline,2hrs,4 hrs,6 hrs,12 hrs,24 hrs
次要结局
未报告次要终点
研究者
DrVenkatesh Soundarya
Sapthagiri Institute Of Medical Sciences And Research Centre
