Effect of Hypnosis on Motor Cortex Excitability
Not Applicable
Completed
- Conditions
- Healthy
- Registration Number
- NCT00416247
- Lead Sponsor
- Rambam Health Care Campus
- Brief Summary
This study is intended to investigate neurophysiological mechanisms of hypnosis using transcranial magnetic stimulation (TMS) and assessment of motor cortex excitability in healthy volunteers under hypnosis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
.
- Healthy volunteers aged 20 to 45 years.
- Hypnotisability above 14 as measured by the Tellegan absorption scale.
Exclusion Criteria
- Psychiatric diagnosis in axis I or axis II;
- Documented history of head injury or seizure disorder;
- Evidence of a disorder which could affect peripheral and central conduction such as multiple sclerosis, motor neuron disease, carpal tunnel syndrome, cervical spondylosis, diabetic neuropathy.
- Any other contraindication to TMS as specified in the safety guidelines for rTMS (Wassermann, 1998) such as cardiac pacemakers or metallic deep brain electrodes.
- Chronic pharmacological treatment.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Cortical Excitability Before and after intervention
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie hypnosis-induced changes in motor cortex excitability measured by TMS?
How does hypnosis compare to pharmacological interventions in modulating motor cortex excitability in healthy subjects?
Are there specific biomarkers that correlate with hypnosis effectiveness on motor cortex plasticity in humans?
What adverse neurological effects have been reported in hypnosis studies using TMS for motor cortex assessment?
How do hypnotic states influence GABAergic neurotransmission and cortical inhibition in motor pathways?
Trial Locations
- Locations (1)
Rambam Medical Center
🇮🇱Haifa, Israel
Rambam Medical Center🇮🇱Haifa, Israel