Effect of Motor Entrainment to Auditory Cues and Music During Walking on Quality of Movement and Perceived Fatigue in Persons With Multiple Sclerosis (PwMS)

Completed

• Conditions: Multiple Sclerosis
• Interventions: Behavioral: auditory cues and music during walking

• Registration Number: NCT03281330
• Lead Sponsor: Hasselt University

Brief Summary

The study investigates the effect of different conditions of auditory cueing and music on walking quality and perceived fatigue in persons with multiple sclerosis compared to healthy controls. The study extends over a four session period, each session lasting maximally 1h30 minutes The experimental conditions include participants walking to music and metronome (at different tempi) for 3minutes and 15 seconds per condition, with a rest period of 3 minutes in between each condition. Non-invasive equipment will be used. participants are equipped with sensors (watch-like straps at the wrists, ankles and across the chest) and are given wireless headphones.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-01
• Study First Submitted: 2017-09-11
• Study First Submitted QC: 2017-09-11
• Study First Posted: 2017-09-13
• Primary Completion: 2018-05-30
• Study Completion: 2018-06-30
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-02
• Last Update Posted: 2018-08-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• diagnosis of MS of >1 year,
• no relapse in the last 1 month,
• ability to walk for 12 minutes without interruption,
• an average usual walking speed between the range of 0.4 and 1.2 m/s.

Exclusion Criteria

• cognitive impairment hindering the understanding and execution of the experimental procedures
• pregnancy
• hearing impairment
• amusia
• beat deafness

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Healthy controls	auditory cues and music during walking	-
persons with Multiple Sclerosis	auditory cues and music during walking	-

Primary Outcome Measures

Name	Time	Method
Spatio-temporal parameters of gait	week 3	Participants wear portable APDM sensors. These sensors are activated during the walking, and record the spatio-temporal parameters of gait.
Parameter's of sychronisation	week 3	Participants have two light ipods attached on their ankles- these are a part of the D-jogger system. The system is activated during the walking, and logs the synchronization parameters

Secondary Outcome Measures

Name	Time	Method
motivation	week 3	he participants is asked: 'how motivating was it to walk to the last particular stimuli (in the metronome condition)/Song (in the music condition) on a scale of 0-5. ) being not motivating at all and 5 being very motivating'.
physical /mental fatigue	week 3	After each experimental condition, the participant is asked 'how tired do you feel in your body on a scale of 0 to 10, 0 being not tired at all and 10 being exhausted'
subjective physical /mental fatigue	week 2	After each experimental condition, the participant is asked 'how tired do you feel in your body on a scale of 0 to 10, 0 being not tired at all and 10 being exhausted'

Trial Locations

Locations (3)

University of Ghent; 🇧🇪 Gent, Belgium

Revalidatie & MS Centrum Overpelt; 🇧🇪 Overpelt, Belgium

Nationaal Multiple Sclerose Center; 🇧🇪 Melsbroek, Belgium